Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  13
• Reference
  J:40894 Panoskaltsis-Mortari A, et al., Genetic and immunological parameters governing in vivo susceptibility/resistance to retrovirally induced murine malignant histiocytosis. J Leukoc Biol. 1998 Oct;64(4):441-50
• ID
  MGI:3036725

Genes

Gene	Assay Type
Mhsvr1	resistance/susceptibility
Pmv9	reported elsewhere
Iapls3-14	reported elsewhere

Notes

• Experiment
  Analysis of the strain distribution pattern of 25 BXD recombinant inbred (RI) strains identified a locus associated with dominant resistance to the malignant histiocytosis sarcoma virus (MHSV). This locus mapped to 57 cM on mouse Chromosome 13 and is named Mhsvr1. Pmv9 (54 cM) and Iapls3-14 (59 cM) are 2 genes showing significant linkage (95.8% probability) to Mhsvr1. Mhsvr1 is syntenic to human chromosome 5q35, a region that is associated with human malignant histiocytosis (MH).