Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  3
• Reference
  J:43555 Ault KA, et al., Genetic control of platelet activation in inbred mouse strains. Platelets. 1997;8(4):235-241
• ID
  MGI:3042395

Genes

Gene	Assay Type
Pact1	visible phenotype
D3Mit7	PCR amplified length variant
D3Nds1	PCR amplified length variant

Notes

• Experiment
  Linkage analysis was performed on 14 SWXJ (SWR/Bm x SJL/Bm) recombinant inbred strains and 20 AKXD (AKR/J x DBA/2J) recombinant inbred strains to identify QTLs associated with platelet activation. Parental strains SJL/Bm and AKR/J exhibit high levels of spontaneous platelet activation compared to parental strains SWR/Bm and DBA/2J. Linkage to the platelet activation phenotype mapped to approximately 27 cM on mouse Chromosome 3 and is named Pact1 (platelet activation 1). Pact1 is linked to D3Mit7 in the SWXJ RI strains and is linked to D3Nds1 in the AKR/J RI strains.