Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  3
• Reference
  J:93070 Brockmann GA, et al., QTLs for pre- and postweaning body weight and body composition in selected mice. Mamm Genome. 2004 Aug;15(8):593-609
• ID
  MGI:3510113

Genes

Gene
Mtbcq1

Notes

• Experiment
  Linkage analysis was performed on 275 animals from a (NMRI8/Fbn x DBA/2OlaHsd)F2 intercross to identify QTLs associated with post-weaning body weight and body composition. Parental strain NMRI8/Fbn is 2.5 times heavier than parental strain DBA/OlaHsd, and also exhibits increased muscle and organ weight at 6 weeks of age and 4.6 times the amount of reproductive fat of DBA/2OlaHsd. 92 microsatellite markers were used for the genome scan.
  
  An interval on mouse Chromosome 3 from 66 cM - 68 cM showed linkage to early body weight at 2 weeks of age. This QTL was designated Bwnd2wk3 and is centered at 68 cM. (Suggestive linkage to body weight at 3 weeks was also observed.) NMRI8/Fbn-derived alleles confer decreased body weight with a dominant mode of inheritanceat Bwnd2wk3.