Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  9
• Reference
  J:93070 Brockmann GA, et al., QTLs for pre- and postweaning body weight and body composition in selected mice. Mamm Genome. 2004 Aug;15(8):593-609
• ID
  MGI:3510159

Genes

Gene
Mtbcq8
Mtbcq8
Mtbcq8
Mtbcq8

Notes

• Experiment
  Linkage analysis was performed on 275 animals from a (NMRI8/Fbn x DBA/2OlaHsd)F2 intercross to identify QTLs associated with post-weaning body weight and body composition. Parental strain NMRI8/Fbn is 2.5 times heavier than parental strain DBA/OlaHsd, and also exhibits increased muscle and organ weight at 6 weeks of age and 4.6 times the amount of reproductive fat of DBA/2OlaHsd. 92 microsatellite markers were used for the genome scan.
  
  An interval on mouse Chromosome 9 from 27 cM - 35 cM showed linkage to body weight at 2, 4, 5, and 6 weeks of age. These QTLs were designated Bwnd2wk6 (27 cM), Bwnd4wk5 (33 cM), Bwnd5wk5 (30 cM), and Bwnd6wk4 (28 cM). (Suggestive linkage to body weight at 3 weeks of age was also observed.) NMRI8/Fbn-derived alleles confer increased body weight with a dominant mode of inheritance at these loci.