Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  8
• Reference
  J:94028 Rocha JL, et al., A large-sample QTL study in mice: III. Reproduction. Mamm Genome. 2004 Nov;15(11):878-86
• ID
  MGI:3512190

Genes

Gene	Assay Type
D8Mit4	PCR amplified length variant
D8Mit31	PCR amplified length variant
Orq3	visible phenotype
D8Mit121	PCR amplified length variant
Orq1	visible phenotype

Notes

• Experiment
  Linkage analysis was performed on 439 pregnant female animals from a (M16i x L6)F2 intercross to identify QTLs associated with reproductive traits. Parental strain M16i exhibits a higher ovulation rate and higher number of live fetuses at 10 weeks of gestation compared to L6, but parental strain L6 exhibits increased total fetal survival rate compared to M16i.
  
  On mouse Chromosome 8, linkage to ovulation rate mapped to 24.9 cM (Orq3, LOD=3.4) and 46.3 cM (Orq1, LOD=3.5). The QTL interval of Orq3 (ovulation rate QTL 3) spans 14 cM - 33 cM and is flanked by markers D8Mit4 and D8Mit31. The QTL interval of Oriq1 spans 33 cM - 55.5 cM and is flanked by markers D8Mit31 and D8Mit121. M16i-derived alleles confer additively inherited increased ovulation rate at Orq3 and Orq1.