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Mapping Data
Experiment
  • Experiment
    TEXT-QTL
  • Chromosome
    14
  • Reference
    J:94352 Volkman SK, et al., Quantitative trait loci for femoral size and shape in a genetically heterogeneous mouse population. J Bone Miner Res. 2003 Aug;18(8):1497-505
  • ID
    MGI:3512971
Genes
GeneAlleleAssay TypeDescription
Fmgty11 visible phenotype
D14Mit170 PCR amplified length variant
Notes
  • Experiment
    487 animals from a heterogeneous stock designated UM-HET3 were analyzed for bone (femur) geometry traits. UM-HET3 is derived from a cross between (BALB/cJ x C57BL/6J)F1 x (C3H/HeJ x DBA/2J)F1. 99 polymorphic markers at an average spacing of 15 cM - 20 cM were used in the genome scan. Nine geometric traits were evaluated for each femur.

    Linkage to standard deviation of outer fiber length (StdOFL) and shape factor (SF) mapped to 63 cM on mouse Chromosome 14 near D14Mit170. This locus is designated Fmgty11. DBA/2J-derived alleles confer increased StdOFL compared to C3H/HeJ-derived alleles, and C3H/HeJ-derived alleles confer increased SF compared to DBA/2J-derived alleles.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory