Mapping Data

Experiment

• Experiment
  TEXT-QTL-Candidate Genes
• Chromosome
  4
• Reference
  J:98587 Hitzemann R, et al., On the integration of alcohol-related quantitative trait loci and gene expression analyses. Alcohol Clin Exp Res. 2004 Oct;28(10):1437-48
• ID
  MGI:3580134

Genes

Gene
Alcw2
Alad

Notes

• Experiment
  Microarray analysis was used to identify genes showing alcohol-induced differential expression between inbred strains C57BL/6J and DBA/2J. These genes were then correlated to 6 previously identified alcohol-related QTLs to identify potential candidate genes. Two different Affymetrix microarrays were used in the analysis. Brain expression data from parental strains and 56 (DBA/2J x C57BL/6J)F2 intercross animals were used for analysis.
  
  On mouse Chromosome 4, the highest priority candidate genes identified for Alcw2 at 40 cM is Alad (30.6 cM). Other candidate genes with a ranking of modest priority were identified but are not listed here.