Mapping Data

Experiment

• Experiment
  TEXT-QTL-Candidate Genes
• Chromosome
  9
• Reference
  J:98587 Hitzemann R, et al., On the integration of alcohol-related quantitative trait loci and gene expression analyses. Alcohol Clin Exp Res. 2004 Oct;28(10):1437-48
• ID
  MGI:3580135

Genes

Gene
Ap5q
Sorl1
Sc5d
Spg21
Arpp19

Notes

• Experiment
  Microarray analysis was used to identify genes showing alcohol-induced differential expression between inbred strains C57BL/6J and DBA/2J. These genes were then correlated to 6 previously identified alcohol-related QTLs to identify potential candidate genes. Two different Affymetrix microarrays were used in the analysis. Brain expression data from parental strains and 56 (DBA/2J x C57BL/6J)F2 intercross animals were used for analysis.
  
  On mouse Chromosome 9, several candidate genes were identified for Ap5q at 26 cM. The highest priority candidate genes identified for Ap5q are Sorl1, Sc5d, Spg21 (40 cM, formerly D9Wsu18e), and Arpp19. Other candidate genes with a ranking of modest priority were identified but are not listed here.