Mapping Data

Experiment

• Experiment
  TEXT-QTL-Candidate Genes
• Chromosome
  19
• Reference
  J:98587 Hitzemann R, et al., On the integration of alcohol-related quantitative trait loci and gene expression analyses. Alcohol Clin Exp Res. 2004 Oct;28(10):1437-48
• ID
  MGI:3580136

Genes

Gene
Alcdp2
Scd1
Shoc2

Notes

• Experiment
  Microarray analysis was used to identify genes showing alcohol-induced differential expression between inbred strains C57BL/6J and DBA/2J. These genes were then correlated to 6 previously identified alcohol-related QTLs to identify potential candidate genes. Two different Affymetrix microarrays were used in the analysis. Brain expression data from parental strains and 56 (DBA/2J x C57BL/6J)F2 intercross animals were used for analysis.
  
  On mouse Chromosome 19, candidate genes for Alcdp2 at 40 cM were identified with modest priority status. These candidate genes are Scd1 (43 cM), Shoc2, Prdx3 (50 cM), and 3 other yet unidentified expressed sequences (ESTs).