Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  1
• Reference
  J:103841 Stylianou IM, et al., Quantitative trait locus analysis for obesity reveals multiple networks of interacting loci. Mamm Genome. 2006 Jan;17(1):22-36
• ID
  MGI:3615173

Genes

Gene	Assay Type
Obwq1	visible phenotype
D1Mit87	PCR amplified length variant

Notes

• Experiment
  Linkage analysis was performed on 513 animals from a (SM/J x NZB/BlNJ)F2 intercross to identify QTL affecting obesity traits. Animals were placed on an atherogenic diet for 16 weeks before phenotyping. Parental strain SM/J exhibits smaller body size but higher adiposity compared to parental strain NZB/BlNJ.
  
  Obwq1 maps to 62 cM on mouse Chromosome 1 near D1Mit87 (LOD=4.3) with the 95% confidence interval spanning approximately 24 cM - 64 cM. NZB/BlNJ-derived alleles at Obwq1 confer increased body weightand mesenteric fat pad weight with a dominant mode of inheritance. Previously identified obesity QTL mapping near Obwq1 are Fatq1 (62 cM) and Obq8 (69.1 cM).