Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  X
• Reference
  J:103841 Stylianou IM, et al., Quantitative trait locus analysis for obesity reveals multiple networks of interacting loci. Mamm Genome. 2006 Jan;17(1):22-36
• ID
  MGI:3615290

Genes

Gene	Assay Type
Obq22	visible phenotype
DXMit1.1	PCR amplified length variant

Notes

• Experiment
  Linkage analysis was performed on 513 animals from a (SM/J x NZB/BlNJ)F2 intercross to identify QTL affecting obesity traits. Animals were placed on an atherogenic diet for 16 weeks before phenotyping. Parental strain SM/J exhibits smaller body size but higher adiposity compared to parental strain NZB/BlNJ.
  
  Obq22 maps to 34 cM on mouse Chromosome X near DXMit1 (LOD=4.2) with a 95% confidence interval spanning 18 cM - 44 cM. NZB/BlNJ-derived alleles confer increased gonadal and retroperitoneal fat pad weights with codominant inheritance. Previously identified obesity QTL Fob4 (37 cM) and Obq6 (16 cM) map near Obq22.