Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  5
• Reference
  J:7417 Peleg L, et al., Genetic control of thymus size in inbred mice. J Hered. 1984 Mar-Apr;75(2):126-30
• ID
  MGI:3615628

Genes

Gene	Assay Type
Tsz1	visible phenotype
Spp1	reported elsewhere

Notes

• Experiment
  Tsz1, a QTL affecting adult thymus size was mapped using 20 BXD (B=C57BL/6J; D=DBA/2J) and 24 AXB/BXA (B=C57BL/6J; A=A/J) recombinant inbred strains. Parental strain C57BL/6J exhibits a 2-fold increase in thymus size compared to parental strains DBA/2J and A/J. The strain distribution pattern of Tsz1 in BXD RI strains showed statistically significant correlation to Spp1 (56 cM) on mouse Chromosome 5. The genetic distance between Tsz1 and Spp1 is estimated to be approximately 8 cM. However, Tsz1 did not show linkage to Gusb (72 cM), the chromosome 5 marker in the AXB/BXA RI strains.