Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  17
• Reference
  J:5355 Oliverio A, et al., Exploratory activity: genetic analysis of its modification by scopolamine and amphetamine. Physiol Behav. 1973 May;10(5):893-9
• ID
  MGI:3615631

Genes

Gene	Assay Type
Scom	visible phenotype
H2	reported elsewhere

Notes

• Experiment
  Inbred strain C57BL/6By exhibits higher short term exploratory activity compared to inbred strain BALB/cBy. However, this phenotype is reversed when animals are administered scopolomine in that BALB/cBy now exhibits higher short term exploratory activitycompared to C57BL/6By. Analysis of 7 CXB (C=BALB/cBy; B=C57BL/6By) recombinant inbred (RI) strains mapped A QTL named Scom (scopolamine modification of exploratory activity) near the H2 locus at 23 cM on mouse Chromosome 17.
  
  A previously identified QTL named Exa (exploratory activity) mapped to mouse Chromosome 4 in congenic line H(w26) derived from BALB/cBy donor and C57BL/6By recipient strains. The congenic exhibits low exploratory activity similar to the BALB/cBy donor strain, indicating that Exa exhibits decreased exploratory activity when derived from BALB/cBy.