Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  5
• Reference
  J:7273 Matossian-Rogers A, et al., Alloimmune interactions of a lymphoproliferative disease-inducer gene Arp and linkage to Pep-7. Immunogenetics. 1983;18(6):639-48
• ID
  MGI:3615648

Genes

Gene	Assay Type
Lap3	reported elsewhere
Arp	visible phenotype

Notes

• Experiment
  Genetic screening of (B10.D2-H2^d x BALB/c)F1 x BALB/c backcross animals revealed linkage between Arp (Arp lymphoid/erythroid hyperplasia) and Lap3 (formerly Pep7) at 67 cM on mouse Chromosome 5. The BALB/c allele of Arp is associated with induction of lymphoproliferative disease. Arp^BALB/c is also associated a Lap3 protein polymorphism exhibiting faster mobility compared to the C57BL/10 variant. Arp interacts with a separate locus named Lus (lymphoid cytostasis suppressor) for development of lymphoproliferative disease.