Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  17
• Reference
  J:7239 Kohno A, et al., Genetic regulation of the class conversion of dsDNA-specific antibodies in (NZB X NZW)F1 hybrid. Immunogenetics. 1983;18(5):513-24
• ID
  MGI:3620191

Genes

Gene	Assay Type
Ads1	visible phenotype
Ads3	visible phenotype
H2	reported elsewhere

Notes

• Experiment
  H2 haplotype analysis of (NZB/NZW)F1 x NZB backcross animals revealed linkage between the NZW-derived H2 allele and increased production of IgG anti-dsDNA autoantibodies. This locus is named Ads3 (anti dsDNA antibody 3). NZB-derived alleles at H2 are also associated with increased production of IgM anti-dsDNA antibodies. This locus is named Ads1 (anti dsDNA antibody 1). Ads1 appears to be closely linked to Agp1, and Ads3 appears to be closely linked to Agp3.