Mapping Data

Experiment

• Experiment
  TEXT-Congenic
• Chromosome
  17
• Reference
  J:7046 Maruyama N, et al., H-2-linked regulation of serum gp70 production in mice. Immunogenetics. 1983;17(5):507-21
• ID
  MGI:3621936

Genes

Gene	Assay Type
Sgp1	visible phenotype
H2	immunological

Notes

• Experiment
  Control of serum gp70 production is believed to be under complex control. The high serum gp70 phenotype was observed in congenic lines B10.D2-H2^d and B10.OL-H2^o1 compared to 12 other C57BL/10-derived H2 congenics. This observation mapped the Sgp1 locus to approximately 19 cM on mouse Chromosome 17. Sgp1 is believed to be closely linked to the H2 locus, but residing outside of it. Sgp1 influences serum gp70 concentrations and gp70 production after lipopolysaccharide (LPS) stimulation.