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Mapping Data
Experiment
  • Experiment
    TEXT-QTL
  • Chromosome
    18
  • Reference
    J:109795 Kenney-Hunt JP, et al., Quantitative trait loci for body size components in mice. Mamm Genome. 2006 Jun;17(6):526-37
  • ID
    MGI:3639989
Genes
GeneAlleleAssay TypeDescription
Bwtn5 visible phenotype
D18Mit17 PCR
Notes
  • Experiment
    Genetic loci associated with long bone length, necropsy body weight, and organ weight were mapped in 1045 animals from a (LG/J x SM/J)F2 intercross. Animals were phenotyped between 70 and 237 days of age, with an average age at sacrifice of 144 days. Twodifferent sets of F2 mice were genotyped for 75 and 96 polymorphic markers across 19 autosomes. 97 single trait QTL were identified. After pleiotropy analysis the 97 loci coalesced into 35 pleiotropic QTLs. Cutoff for statistical significance is LPR=3.49but all pleiotropic loci listed in the reference are reported here.

    On mouse Chromosome 18, Bwtn5 (body weight at necropsy 5) mapped to 20 cM near D18Mit17 (LPR=2.86). Previously identified QTL Adip8 at 20 cM may be identical to this locus. The Bwtn5 confidence interval spans 0 cM - 26 cM.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory