Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  7
• Reference
  J:105260 Bermingham JR Jr, et al., The claw paw mutation reveals a role for Lgi4 in peripheral nerve development. Nat Neurosci. 2006 Jan;9(1):76-84
• ID
  MGI:3654304

Genes

Gene	Description
D7Mit266
D7Mit246
D7Mit344
D7Mit343
D7Mri1
D7Mri2
D7Mri3
Lgi4	clp
D7Mit155
D7Mit224
D7Mit55
D7Mit78
D7Mit310

Notes

• Experiment
  MGI shows D7Mri3 segregating without recombination with Lgi4^clp, some mice may not have been typed for both loci. In fine mapping authors show the clp phenotype as mapping distal to D7Mri3 and proximal of D7Mit155. clp was found to be a mutant form of Lgi4.Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, sexes unspecified or combined
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c>
• Strain
  (C57BL/6J x CAST/Ei)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Allele 1
  b from C57BL/6J
• Allele 2
  c from CAST/Ei

CROSS Data

MC #mice	D7Mit266	D7Mit246	D7Mit344	D7Mit343	D7Mri1	D7Mri2	D7Mri3	Lgi4	D7Mit155	D7Mit224	D7Mit55	D7Mit78	D7Mit310
271	b	b	b	b	b	b	b	b	b	b	b	b	b
207	c	c	c	c	c	c	c	c	c	c	c	c	c
7	c	b	b	b	b	b	b	b	b	b	b	b	b
2	c	c	c	c	c	c	c	c	b	b	b	b	b
2	c	c	c	c	c	c	c	c	c	.	.	b	b
2	c	c	c	c	c	c	c	c	c	c	c	b	b
10	c	c	c	c	c	c	c	c	c	c	c	c	b
10	b	c	c	c	c	c	c	c	c	c	c	c	c
1	b	b	b	b	b	b	c	c	c	.	.	c	c
1	b	b	b	b	b	b	b	b	c	.	.	c	c
1	b	b	b	b	b	b	b	b	.	.	.	c	c
1	b	b	b	b	b	b	b	b	b	.	.	c	c
15	b	b	b	b	b	b	b	b	b	b	b	b	c

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D7Mit266	D7Mit246	17	530	3.208	0.765
D7Mit246	D7Mit344	0	530	0.000	0.000
D7Mit344	D7Mit343	0	530	0.000	0.000
D7Mit343	D7Mri1	0	530	0.000	0.000
D7Mri1	D7Mri2	0	530	0.000	0.000
D7Mri2	D7Mri3	1	530	0.189	0.189
D7Mri3	Lgi4	0	530	0.000	0.000
Lgi4	D7Mit155	3	529	0.567	0.326
D7Mit155	D7Mit224	0	524	0.000	0.000
D7Mit224	D7Mit55	0	524	0.000	0.000
D7Mit55	D7Mit78	2	524	0.382	0.269
D7Mit78	D7Mit310	25	530	4.717	0.921