Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  17
• Reference
  J:6051 van Nie R, et al., A new H-2-linked mutation, rds, causing retinal degeneration in the mouse. Tissue Antigens. 1978 Aug;12(2):106-8
• ID
  MGI:37021

Genes

Gene	Allele
H2
Prph2	Prph2^Rd2

Notes

• Reference
  Congenic strain 0IR/A has a O20/A genetic background carrying H-2^q and the + allele for rd-2 from DBA/A. This suggestion of linkage was confirmed using backcrosses. In 35 mice from a (O20/A x GRS/A) x O20 backcross, 19 rd-2/rd-2 progeny all rejected grafts of a mammary tumor of GRS/A origin. Those with normal retinas did not reject the tumor. Two other crosses demonstrated H-2 and rd-2 linkage. Revised gene symbol: rd-2 (formelry Rds).
• Experiment
  Sex of segregating parent not given.Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, sexes unspecified or combined
• Female Parent
  H-2<pz> rd-2/H-2<dx> +
• Strain
  (O20/A x GRS/A)F1
• Male Parent
  H-2<pz> rd-2/H-2<pz> rd-2
• Strain
  O20/A

CROSS Data

MC #mice	H2	Prph2
18	H-2<pz>	rd-2
30	H-2<dx>	+
1	H-2<pz>	+
1	H-2<dx>	rd-2

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
H2	Prph2	2	50	4.000	2.771