Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  1
• Reference
  J:9261 Potter M, et al., Genes on chromosomes 1 and 4 in the mouse are associated with repair of radiation-induced chromatin damage. Genomics. 1988 Apr;2(3):257-62
• ID
  MGI:37045

Genes

Gene
Bcl2
Rep1
Pepc

Notes

• Experiment
  BALB/cAn has inefficient repair phenotype of X-irradiation chromatin damage (Rep1b Rep2b) whereas DBA/2N has efficient repair (Rep1a Rep2a). These genes were mapped to chromosomes 1 and 4 respectively by congenic strains C.D2-Idh1b Pepc^b (also carryingDBA/2N alleles of Cryg-1 and Bcl2), C.D2-Pepc^b (also carryng DBA/2N allele of Bcl2) and C.D2-Fv-1n (also carrying DBA/2N allele of Pnd) that displayed the DBA/2N efficient repair phenotype. Strains C.D2-DAG(Ly-6) and C.D2-Qa-2+ were BALB/cAn type in their repair phenotype.