HYBRID Mapping MGI Mouse MGI:37258

Mapping Data

Experiment

HYBRID
Chromosome

11
Reference

J:7957 Silver J, et al., Erbb is linked to the alpha-globin locus on mouse chromosome 11. Mol Cell Biol. 1985 Jul;5(7):1784-6
ID

MGI:37258

Gene	Allele	Assay Type	Description
Egfr

Reference

Twelve partially congenic mice, where Hba-thal was being transferred to an inbred background, were analyzed for Erbb. Four were recombinant between Hba and Erbb (representing 76 backcrosses) indicating close linkage (5% recombination) of Hba and Erbb.
Experiment

Somatic cell hybrids constructed using Chinese hamster and mouse cell lines. The mouse chromosome complement was determined by karyotype and isozyme analysis. Erbb was typed using HindIII and PstI digested DNAs probed with a human c-erb-B probe.

HYBRID Data

Chromosome	+/-	-/-
1	10	6
2	11	4
3	6	6
4	8	9
5	5	10
6	6	7
7	15	3
8	6	9
9	8	10
10	5	12
11	0	14
12	9	4
13	6	6
14	6	10
15	13	1
16	8	7
17	10	6
18	10	4
19	10	7
X	6	9

Chromosome	+/-	-/-
1	10	6
2	11	4
3	6	6
4	8	9
5	5	10
6	6	7
7	15	3
8	6	9
9	8	10
10	5	12
11	0	14
12	9	4
13	6	6
14	6	10
15	13	1
16	8	7
17	10	6
18	10	4
19	10	7
X	6	9

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Chromosome	+/-	-/-
1	10	6
2	11	4
3	6	6
4	8	9
5	5	10
6	6	7
7	15	3
8	6	9
9	8	10
10	5	12
11	0	14
12	9	4
13	6	6
14	6	10
15	13	1
16	8	7
17	10	6
18	10	4
19	10	7
X	6	9

Chromosome	+/-	-/-
1	10	6
2	11	4
3	6	6
4	8	9
5	5	10
6	6	7
7	15	3
8	6	9
9	8	10
10	5	12
11	0	14
12	9	4
13	6	6
14	6	10
15	13	1
16	8	7
17	10	6
18	10	4
19	10	7
X	6	9