Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  7
• Reference
  J:131363 Haraldsson MK, et al., The lupus-related Lmb3 locus contains a disease-suppressing Coronin-1A gene mutation. Immunity. 2008 Jan;28(1):40-51
• ID
  MGI:3773684

Genes

Gene
Coro1a
Coro1a
D7Sri317
D7Sri88

Notes

• Experiment
  Using 2500 meioses in combination with MRL.B6-Lmb3 Fas-lpr
  subcongenic mice the QTL Lmb3 was mapped to a 0.9 Mb interval of mouse Chromosome 7 between D7Sri317 and D7Sri88 with a physical location between 125.71 Mb and 126.66 Mb ( Assembly v36). Importantly the authors provide evidence that a mutant Corola1 locus could be the causative locus underlying the Lmb3 phenotype.