Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  2
• Reference
  J:136510 Kearney JA, et al., Severe epilepsy resulting from genetic interaction between Scn2a and Kcnq2. Hum Mol Genet. 2006 Mar 15;15(6):1043-8
• ID
  MGI:3822487

Genes

Gene	Assay Type	Description
D2Mit148	PCR
Kcnq2	visible phenotype	Nmf134

Notes

• Experiment
  The dominant Nmf134 mutation was mapped using 17 affected and 24 unaffected N2 backcross mice. Nmf134 mapped to distal chromosome 2 by linkage with the markers D2Mit148 and D2Frk1. A peak LOD score of 4.2 was obtained DNA marker D2Frk1 which was located within an intron of the Kcnq2 gene.