Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  18
• Reference
  J:140028 Zhang MC, et al., Mast cell hyperplasia in the skin of Dsg4-deficient hypotrichosis mice, which are long-living mutants of lupus-prone mice. Immunogenetics. 2008 Oct;60(10):599-607
• ID
  MGI:3822912

Genes

Gene	Assay Type	Description
D18Mit146	PCR
D18Mit117	PCR
D18Mit83	PCR
Dsg4	visible phenotype	Dsg4
D18Mit14	PCR

Notes

• Experiment
  The Autors mapped the hage mutation induced by the insertion of an early transposon II-beta into intron 8 of the Dsg4 locus. The 5,543-bp ETn II-Beta was integrated into intron 8, 203 bp away from the initial nucleotide of intron 8.Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, sexes unspecified or combined
• Female Parent
  <e> <e> <e> <e> <e>/<m> <m> <m> <m> <m>
• Strain
  (EOD x MSM)F1
• Male Parent
  <e> <e> <e> <e> <e>/<e> <e> <e> <e> <e>
• Strain
  EOD
• Allele 1
  e from EOD
• Allele 2
  m from MSM

CROSS Data

MC #mice	D18Mit146	D18Mit117	D18Mit83	Dsg4	D18Mit14
35	e	e	e	e	e
47	m	m	m	m	m
2	m	e	e	e	e
2	e	m	m	m	m
10	e	e	e	e	m
8	m	m	m	m	e
1	e	e	m	m	m

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D18Mit146	D18Mit117	4	105	3.810	1.868
D18Mit117	D18Mit83	1	105	0.952	0.948
D18Mit83	Dsg4	0	105	0.000	0.000
Dsg4	D18Mit14	18	105	17.143	3.678