Mapping Data

Experiment

• Experiment
  HYBRID
• Chromosome
  5
• Reference
  J:6116 Kozak CA, et al., Genetic mapping of the ecotropic murine leukemia virus-inducing locus of BALB/c mouse to chromosome 5. Science. 1979 Apr 6;204(4388):69-71
• ID
  MGI:38251

Genes

Gene
Pgm2

Notes

• Reference
  Revised gene symbols: Pep-3 (formerly Dip-1), Pep-1 (formerly Dip-2), Pep-2 (formerly Trip) and Emv-1 (formerly Cv-1).
• Experiment
  Somatic cell hybrids were from fusions of BALB/c peritoneal cells and Chinese hamster cell line E36. Hybrids were tested for ecotropic virus induction, Emv-1, and expression of Pep-3, Pep-1, Pep-2, Pgm-1, Pgm-2, Gpi-1, Np-1, Mod-1, Gr-1, Tpi, and Hprt. Emv-1 segregated with only Pgm-1 on Chromosome 5. The 3 discordant clones were assumed to be false discrepancies based on weak enzyme activity and trace virus amounts.

HYBRID

• Concordance
  markers

HYBRID Data

Symbols	+/+	+/-	-/+	-/-
Pgm2	14	1	2	15