Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  13
• Reference
  J:147462 Norgard EA, et al., Replication of long-bone length QTL in the F(9)-F (10) LG,SM advanced intercross. Mamm Genome. 2009 Apr;20(4):224-35
• ID
  MGI:3847099

Genes

Gene	Assay Type
Lbn14	visible phenotype

Notes

• Experiment
  Advanced intercross lines derived from LG/J and SM/J parental inbred strains at the F9 (n=150) and F10 (n=1305) generations were used to confirm and refine previously identified QTL (from F2-F3 generations) for long bone traits and identify novel geneticloci and interacting QTL. Animals were phenotyped between 12 and 40 weeks of age and genotyped at 1470 polymorphic SNP loci. The average distance between markers is 1.66 Mb. Long bone measurements were taken for the right-side tibia, femur, humerus and ulna. Eighty-one single-trait QTL were detected in this study, which includes 27 previously identified long bone loci. Thirteen novel pleiotropic loci were detected.
  
  A novel QTL linked to all four bone length traits mapped to 59 cM on mouse Chromosome 13.This locus is named Lbn14 (lone bones 14). Lbn14 is associated with humerus length (LPR=11.66), femur length (LPR=9.72), tibia length (LPR=13.06) and ulna length (LPR=19.5).