Mapping Data

Experiment

• Experiment
  TEXT-Cytogenetic Localization
• Chromosome
  11
• Reference
  J:7526 Zabel BU, et al., Cellular homologs of the avian erythroblastosis virus erb-A and erb-B genes are syntenic in mouse but asyntenic in man. Proc Natl Acad Sci U S A. 1984 Aug;81(15):4874-8
• ID
  MGI:38860

Genes

Gene
Egfr
Thra
Galk1
Tk1

Notes

• Experiment
  Somatic cell hybrids between mouse spleen cells and Chinese hamster Dona3 cell (PBH series) were analyzed. All hybrids were positive for the Chromosome 11 marker Tk1, but only some were positive for Chromosome 11 Galk1, suggesting that a Chromosome 11 deletion had occurred during cell passage. Six of these hybrids were probed for Erbb and Erba by filter hybridization. Two were positive for Erba and Tk1 but negative for Erbb and Galk1; two were positive for Tk1 and Galk1, but negative for Erbb and Erba; and twowere positive for Tk1 only. Erbb and Galk1 segregated independantly, suggesting that they may be located on opposite sides of Tk1 on Chromosome 11.