Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  16
• Reference
  J:10494 Pash J, et al., Chromosomal protein HMG-14 gene maps to the Down syndrome region of human chromosome 21 and is overexpressed in mouse trisomy 16. Proc Natl Acad Sci U S A. 1990 May;87(10):3836-40
• ID
  MGI:39206

Genes

Gene	Assay Type	Description
Hmgn1	Northern analysis	HGM14 cDNA

Notes

• Experiment
  Ts16 (trisomy 16) and normal embryos from a mating between C57BL/6N females and Rb(16.17)32Lub/Rb(11.16)2H males were analyzed. Trisomic embryos expressed Hmgn1 at a level indicative of three gene copies based on Northern analysis of mRNA levels and on immunoblots of protein. The expression of Hmgn1 an unlinked gene, was measured as the control. These data suggest that Hmgn1 maps to Chromosome 16 and are consistent with the mapping of the human homolog to Chromosome 21.