Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  9
• Reference
  J:10294 Kingsley DM, et al., Genetic ablation of a mouse gene expressed specifically in brain. EMBO J. 1990 Feb;9(2):395-9
• ID
  MGI:39249

Genes

Gene	Allele	Assay Type	Description
Myo5a	Myo5a^d	visible phenotype
D9Citb3		Southern analysis	cDNA 1B1075
Bmp5	Bmp5^se	visible phenotype

Notes

• Reference
  Authors uses pl-4 for pnlf4.
• Experiment
  Physical localizaton of D9Citb3 was accomplished by complimentation studies of radiation induced deletions in the dilute (d) region of Chromosome 9. There were 48 deletions analyzed; the position of D9Citb3 was suggested as distal to prenatal lethal factor 4(pnlf4) and proximal to se. Three matings between radiation induced deletions Da1 and Db1 (+ se^Da1/d +) x (+ se^Db1/d +) produced progeny that confirmed that D9Citb3 is near se and is essential for viability. D9Citb3, nl2, and pnlfl4 are within 0.16 cM in the d - se region and, based on average genetic and physical map correspondence may represent as little as 200-300 kb of DNA.