Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  17
• Reference
  J:10054 Brorson KA, et al., Analysis of a new class I gene mapping to the Hmt region of the mouse. Immunogenetics. 1989;30(4):273-83
• ID
  MGI:39729

Genes

Gene	Assay Type	Description
H2-K1	immunological	serotyping
Qa2	immunological	serotyping
H2-T18	immunological	serotyping
H2-Q1	immunological	cytotoxic T lymphocytes
H2-M2	Southern analysis	Thy19.4 3' genomic
H2-M3	immunological	cytotoxic T lymphocytes
Crisp2	Southern analysis

Notes

• Reference
  Authors use Thy19.4 for the H-2M2 locus.
• Experiment
  The C3H recombinant congenic strains R4-e and R4-l were used to map H-2M2. These strains carry the alleles for H-2K, Qa2 (now subdivided into three loci; H2-Q7, H2-Q8, H2-Q9), H2-T18 and Qa1 from the C3H host strain and the H-2M2 and H-2M3 alleles with the CAS3 donor strain, implying that H-2M2 and H-2M3 are distal to Qa1. Strain R4-l has an additional recombination breakpoint between H-2M3 and Crisp2, placing H-2M2 and H-2M3 between Qa1 and Crisp2.