Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  6
• Reference
  J:2955 Moore KJ, et al., Chromosomal localization of three pulmonary surfactant protein genes in the mouse. Genomics. 1992 Feb;12(2):388-93
• ID
  MGI:39773

Genes

Gene	Assay Type	Description
Hoxa5	reported elsewhere	Siracusa, et al., Genomics 10:313-326, 1991
Cbl-ps1	reported elsewhere	Regnier, et al., J Virol 63:3678-3682, 1989
Igk	reported elsewhere	Regnier, et al., J Virol 63:3678-3682, 1989
Sftpb	Southern analysis	p16.2e cDNA
Actg2	reported elsewhere	Justice, et al., Genetics 125:855-866, 1990
Raf1	reported elsewhere	deLapeyriere, et al., Oncogene 5:823-831, 1990

Notes

• Reference
  Revised gene symbol: Hoxa5 (formerly Hox-1.3).
• Experiment
  This article reports a multipoint backcross typed for all loci in 55 mice and additional mice typed for only some of the loci. These additional mice appear as 2-point data.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Hoxa5	Cbl-ps1	Igk	Sftpb	Actg2	Raf1
16	b	b	b	b	b	b
21	s	s	s	s	s	s
1	b	s	s	s	s	s
0	s	b	b	b	b	b
1	b	b	s	s	s	s
0	s	s	b	b	b	b
1	b	b	b	s	s	s
0	s	s	s	b	b	b
2	b	b	b	b	s	s
0	s	s	s	s	b	b
8	b	b	b	b	b	s
5	s	s	s	s	s	b

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Hoxa5	Cbl-ps1	3	101
Cbl-ps1	Igk	2	99
Igk	Sftpb	0	97
Sftpb	Actg2	0	22
Actg2	Raf1	4	35

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Hoxa5	Cbl-ps1	4	159	2.516	1.242
Cbl-ps1	Igk	3	156	1.923	1.100
Igk	Sftpb	1	152	0.658	0.656
Sftpb	Actg2	2	77	2.597	1.813
Actg2	Raf1	17	94	18.085	3.970