Mapping Data

Experiment

• Experiment
  TEXT-Cytogenetic Localization
• Chromosome
  11
• Reference
  J:7154 Leinwand LA, et al., Multigene family for sarcomeric myosin heavy chain in mouse and human DNA: localization on a single chromosome. Science. 1983 Aug 19;221(4612):766-9
• ID
  MGI:40214

Genes

Gene	Assay Type	Description
Myhs	Southern analysis	pMHC25
Galk1	enzyme activity
Tk1	enzyme activity

Notes

• Experiment
  Somatic cell hybrids were from fusion of rat Tk1 deficient cell line FT-1 with mouse cells. Hybrid cells were grown in HAT medium which selects for the expression of mouse Chromosome 11 genes Galk1 and Tk1. HindIII genomic digests from these selected hybrids showed positive hybridization for Mhys. The only mouse chromosome present in the hybrids was Chromosome 11 indicating that Myhs, Galk1 and Tk1 are located on this chromosome.