Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  2
• Reference
  J:10580 Oettinger MA, et al., RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science. 1990 Jun 22;248(4962):1517-23
• ID
  MGI:40548

Genes

Gene	Assay Type
Rag1	overlapping clones
Rag2	overlapping clones

Notes

• Experiment
  V(D)J recombination was determined to be controlled by two genes, Rag-1 and Rag-2, on Chromosome 2. These genes are contained on a single 18kb genomic clone 12C.2. A walk from Rag-2 to Rag-1 on clone 12C.2 showed that the loci are 8kb apart. Expression studies demonstrated that Rag-1 are Rag-2 are convergently transcribed.