Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  11
• Reference
  J:15298 Roberts M, et al., Mapping of genes controlling Leishmania major infection in CXS recombinant inbred mice. Eur J Immunogenet. 1993 Oct;20(5):349-62
• ID
  MGI:40598

Genes

Gene	Assay Type
Il3	reported elsewhere
B4galnt2	reported elsewhere
Hoxb	reported elsewhere
Ccl2	reported elsewhere
Mtv3	reported elsewhere
Es3	reported elsewhere
Scl1	resistance/susceptibility

Notes

• Experiment
  Leishmania major infection in mice is controlled by genes on mouse chromosomes. Lesion diameter, spleen weight and liver parasite load were the parameters measured to show significant linkage to Chromosome 11, however no uniform strain distribution pattern was obtained across all experiments. One such locus, Scl1 was mapped in CXS RI lines to markers Il3, B4galnt2, Hoxb, Ccl2, Mtv3 and Es3 spanning 41 cM of Chromosome 11. Scl1 was not positioned with respect to the marker loci.