Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  7
• Reference
  J:912 Avraham KB, et al., Murine chromosomal location of four hepatocyte-enriched transcription factors: HNF-3 alpha, HNF-3 beta, HNF-3 gamma, and HNF-4. Genomics. 1992 Jun;13(2):264-8
• ID
  MGI:40872

Genes

Gene	Assay Type	Description
Tpi-rs3	reported elsewhere	Siracusa, et al., Genetics 127:169-179, 1991
Foxa3	Southern analysis	HNF-3(gamma)
Tgfb1	reported elsewhere	Dickinson, et al.,m Genomics 6:505-520, 1990
Gpi1	reported elsewhere

Notes

• Reference
  Revised gene symbols Hck, Hnf3a, Hnf3b, Hnf3g, Tcf-4 and Tpi-rs3 (formerly Hck-1, Tcf-3a Tcf-3b, Tcf-3g, Hnf-4 and Tpi-3 respectively).
• Experiment
  Data for 173 mice are presented. Up to 189 mice were analyzed for some pairs of markers producing the following statement of order and distance: centromere - Tpi-rs3 - 0.5 +/- 0.5cM - Tcf-3g - 0.6 +/- 0.6cM - Tgfb-1- 4.5 +/- 1.6cM - Gpi-1Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b>/<s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b>/<b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Tpi-rs3	Foxa3	Tgfb1	Gpi1
87	b	b	b	b
77	s	s	s	s
0	s	b	b	b
0	b	s	s	s
1	s	s	b	b
0	b	b	s	s
5	s	s	s	b
3	b	b	b	s

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Tpi-rs3	Foxa3	1	15
Foxa3	Tgfb1	0	2
Tgfb1	Gpi1	0	5

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Tpi-rs3	Foxa3	1	189	0.529	0.528
Foxa3	Tgfb1	1	175	0.571	0.570
Tgfb1	Gpi1	8	178	4.494	1.553