Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  2
• Reference
  J:4326 Carlson GA, et al., Delimiting the location of the scrapie prion incubation time gene on chromosome 2 of the mouse. Genetics. 1993 Apr;133(4):979-88
• ID
  MGI:41684

Genes

Gene	Allele	Assay Type	Description
B2m		Southern analysis	B2m genomic
Il1a		Southern analysis	pIL-1 1301
Tgm3		visible phenotype
Prnp		Southern analysis	hamster cDNA
Pax1	Pax1^un	Southern analysis	pSPT19

Notes

• Reference
  Authors use Spr8 for Gpcr8.
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <i> <i> <i> <i> <i>/<b> <b> <b> <b> <b>
• Strain
  B6.I/Co x B10.UW/Sn
• Male Parent
  <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b>
• Strain
  B10.UW/Sn
• Allele 1
  i from B6.I/Co
• Allele 2
  b from B10.UW/Sn

CROSS Data

MC #mice	B2m	Il1a	Tgm3	Prnp	Pax1
90	i	i	i	i	i
45	b	b	b	b	b
6	b	b	b	b	i
3	i	i	i	i	b
3	b	b	b	i	i
2	i	i	i	b	b
1	b	b	i	i	i
0	i	i	b	b	b
3	b	i	i	i	i
0	i	b	b	b	b

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Tgm3	Prnp	1	297
Prnp	Pax1	9	289

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
B2m	Il1a	3	153	1.961	1.121
Il1a	Tgm3	1	153	0.654	0.651
Tgm3	Prnp	6	451	1.330	0.539
Prnp	Pax1	18	451	3.991	0.922