Mapping Data

Experiment

• Experiment
  RI
• Chromosome
  10
• Reference
  J:4406 Taylor RG, et al., Identification of the mutation in murine histidinemia (his) and genetic mapping of the murine histidase locus (Hal) on chromosome 10. Genomics. 1993 Apr;16(1):231-40
• ID
  MGI:41703

Genes

Gene	Assay Type	Description
D10Mit10	PCR amplified length variant	M7
Hal	Southern analysis	pHAL-m4
Gad1-ps	reported elsewhere	Brilliant, et al., Genomics 6:115-122, 1990
Mdm1	reported elsewhere	Taylor, et al., Mamm Genome 3:700-704, 1992

Notes

• Reference
  Authors suggest his and Hsd may be alleles at the Hal locus.
• Experiment
  Among 50 RI strains (25 BXD, 13 CXB, 12 BXH) only BXH-14 showed recombination between D10Mit10 and Hal yielding a recombination frequency of 0.0052.

RI

• Origin
  C57BL/6J x C3H/HeJ
• Designation
  BXH
• Abbreviation 1
  B
• Abbreviation 2
  H

RI Data (columns show RI Lines sampled)

Marker	2	3	4	6	7	8	9	10	11	12	14	19
D10Mit10	B	H	B	H	H	B	H	H	B	H	H	H
Hal	B	H	B	H	H	B	H	H	B	H	B	H
Gad1-ps	B	H	B	H	H	H	H	H	B	H	B	H
Mdm1	B	B	B	B	H	H	H	H	B	H	B	H

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D10Mit10	Hal	1	12	2.381	2.605
Hal	Gad1-ps	1	12	2.381	2.605
Gad1-ps	Mdm1	2	12	5.556	4.781