Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  17
• Reference
  J:7083 Paterniti JR Jr, et al., Combined lipase deficiency (cld): a lethal mutation on chromosome 17 of the mouse. Science. 1983 Jul 8;221(4606):167-9
• ID
  MGI:41969

Genes

Gene	Assay Type
T	visible phenotype
Lmf1	enzyme activity
Itpr3	visible phenotype

Notes

• Experiment
  Crosses involving T Itpr3^tf carrying mice mated to mice carrying the t^w73 haplotype were informative in uncovering the cld gene. Homozygous cld/cld causes hyperchylomicronemia. T cld +/+ +Itpr3^tf mice crossed to + + +/t^w73 cld + mice produced4 genotypes, 3 of which were normal and one of which was affected. The cld locus thus maps very close to Itpr3^tf.