Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  X
• Reference
  J:7792 Cohen DI, et al., Isolation of a cDNA clone corresponding to an X-linked gene family (XLR) closely linked to the murine immunodeficiency disorder xid. Nature. 1985 Mar 28-Apr 3;314(6009):369-72
• ID
  MGI:42280

Genes

Gene	Allele	Assay Type	Description
Xlr		Southern analysis	pX310
Btk	Btk^xid	reported elsewhere

Notes

• Experiment
  Strains that were made congenic by introducing the xid mutation onto the MRL, BXSB and NZB backgrounds were tested to determine if Xlr gene were cotransferred with xid. Restriction analysis of genomic DNA from the congenic strains indicate that Xlr was transferred with xid and are linked within 5-10 cM. It is important to note that the Xlr probe hybridizes to 10-14 bands of mouse DNA and is thus recognized as a family of genes.