Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  19
• Reference
  J:3304 Watson ML, et al., Genetic analysis of MRL-lpr mice: relationship of the Fas apoptosis gene to disease manifestations and renal disease-modifying loci. J Exp Med. 1992 Dec 1;176(6):1645-56
• ID
  MGI:42371

Genes

Gene	Assay Type	Description
D19Sel3	Southern analysis	MJ55
Fas	Southern analysis	FasL1R2
Ide	Southern analysis	Ide-pSRalph a

Notes

• Experiment
  Some overlap exist among crosses. These data reflect 39 of 182 mice examined. Only phenotypic lpr/lpr mice were included.Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <m> <m> <m>/<c> <c> <c>
• Strain
  (MRL/MpJ-Fas x CAST/Ei)F1
• Male Parent
  <m> <m> <m>/<m> <m> <m>
• Strain
  MRL/MpJ-Fas/J
• Allele 1
  m from MRL/MpJ-Fas/J
• Allele 2
  c from CAST/EiJ

CROSS Data

MC #mice	D19Sel3	Fas	Ide
35	m	m	m
0	c	c	c
0	m	c	c
3	c	m	m
1	m	m	c
0	c	c	m

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D19Sel3	Fas	3	39	7.692	4.267
Fas	Ide	1	39	2.564	2.531