Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  2
• Reference
  J:12911 Michaud EJ, et al., The embryonic lethality of homozygous lethal yellow mice (Ay/Ay) is associated with the disruption of a novel RNA-binding protein. Genes Dev. 1993 Jul;7(7A):1203-13
• ID
  MGI:42478

Genes

Gene	Assay Type
Raly	restriction analysis
a	restriction analysis

Notes

• Experiment
  In the F1 cross between M. spretus and M. musculus, a unique restriction fragment revealed no crossovers (0/80) between Raly and a sequences, indicating tight linkage on Chromosome 2. Using polymorphisms, the authors showed the 3' end of the Raly gene is deleted in the A^y allele and this deletion is between the a gene and the 5' end of the Raly gene. Preliminary and unpublished work by E.J. Michaud, et al., use physical mapping to show the 5' end of Raly lies a maximum of 300kb 5' to a.