Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  1
• Reference
  J:15235 Mock BA, et al., Genetic mapping of tumor susceptibility genes involved in mouse plasmacytomagenesis. Proc Natl Acad Sci U S A. 1993 Oct 15;90(20):9499-503
• ID
  MGI:42669

Genes

Gene	Assay Type	Description
Pctm	resistance/susceptibility
Fcgr2b	Southern analysis	Fcgr2 probe

Notes

• Experiment
  Chi square values for mice derived in the intraspecific backcross BALB/cAnPt females x (BALB/cAnPt x DBA/2N)F1 males indicate a potential linkage between Pcts2 and Chromosome 1 marker Fcgr2. Additional markers need to be tested to confirm/reject linkage.
  
  Heterozygosity at Pctm is associated with susceptibility to pristane-induced plasmacytomas, whereas homozygosity for BALB/cAnPt-derived alleles at this locus is associated with resistance.