Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  11
• Reference
  J:1905 Takahashi Y, et al., Mapping of the nu gene using congenic nude strains and in situ hybridization. J Exp Med. 1992 Mar 1;175(3):873-6
• ID
  MGI:42690

Genes

Gene	Allele	Assay Type	Description
Il3		Southern analysis	Il3 cDNA
Myhs		Southern analysis	Myhs cDNA1
Chrnb1		Southern analysis	Acrb cDNA
Foxn1	Foxn1^nu	visible phenotype
Evi2a		Southern analysis	p597.1
Mpo		Southern analysis	Mpo cDNA1
Hoxb5		Southern analysis	Hox-2.1 cDNA

Notes

• Experiment
  AKR/Ms, BALB/c and C57BL/6N congenic nude mice and their inbred partners were analyzed using Southern analysis to determine a physical location for the nude locus relative to six Chromosome 11 genetic markers. As ordered the markers analyzed included Il3, Myhs, Chrnb1, Evi2a, Mpo, and Hoxb5. Informative RFLVs were used to demonstrate that the nude locus lies within a 9 cM region between Acrb and Mpo. This region includes Evi2a and excludes Chrnb1 and Mpo.