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Mapping Data
Experiment
  • Experiment
    CROSS
  • Chromosome
    6
  • Reference
    J:12780 Jones JM, et al., mnd2: a new mouse model of inherited motor neuron disease. Genomics. 1993 Jun;16(3):669-77
  • ID
    MGI:42810
Genes
GeneAlleleAssay TypeDescription
Tcrb PCR amplified length variant
D6Mit16 PCR amplified length variant D11
Sftpb Southern analysis Sftp-3 probe
D6Mit4 PCR amplified length variant M239
Htra2 visible phenotype
D6Mit6 PCR amplified length variant M259
D6Mit9 PCR amplified length variant L23
D6Rck132 Southern analysis D6Rck132
D6Mit11 PCR amplified length variant M170
Raf1 Southern analysis Raf-1 probe 1
D6Mit12 PCR amplified length variant M11
D6Mit14 PCR amplified length variant M190
Notes
  • Reference
    Possible error in figure 2, where only 49 mice are reported as being typed between markers D6Mit12 and D6Mit14.
  • Experiment
    Line 283 originated from a (C57BL/6J x C3H/He)F2 founder and is maintained by continous backcross onto C57BL/6J. Line 283, which carries mnd2 mutation, was used in the following linkage crosses: (CAST/Ei x 283)F1 mice were mated together and 23 F2 and mnd2/mnd2 offspring were analyzed; and line 283-mnd2/+ mice were crossed to (283-mnd2/+ x CAST/Rk)F1 mice and 8 N2 mnd2/mnd2 offspring were analyzed. Data reflect the number of chromosomes analyzed.
CROSS
  • Type
    Intercross, treated like backcross(i.e. # chromosomes scored)
  • Female Parent
    <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c>
  • Strain
    CAST/Ei x C57BL/6J-Tg.283-Htra2/+ or Tg.283-Htra2/+ +
  • Male Parent
    <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
  • Strain
    CAST/Ei x C57BL/6J-Tg.283-Htra2/+ or Tg.283-Htra2/+ x CAST/Rk +
  • Allele 1
    b from C57BL/6J
  • Allele 2
    c from CAST/EiJ
CROSS Data
MC #mice Tcrb D6Mit16 Sftpb D6Mit4 Htra2 D6Mit6 D6Mit9 D6Rck132 D6Mit11 Raf1 D6Mit12 D6Mit14
35 b b b b b b b b b b b b
5 c b b b b b b b b b b b
1 c c b b b b b b b b b b
2 c c c b b b b b b b b b
2 c c c c b b b b b b b b
1 b b b b b c c c c c c c
1 b b b b b b b c c c c c
2 b b b b b b b b c c c c
1 b b b b b b b b b b c c
4 b b b b b b b b b b b c
Additional Mice Typed Only for Specific Pairs of Loci
Marker 1 Marker 2 # Recombinants # Parentals
D6Mit16 Sftpb 0 16
Sftpb D6Mit4 0 10
D6Mit4 Htra2 1 7
Htra2 D6Mit6 0 10
D6Mit9 D6Rck132 0 4
D6Rck132 Raf1 0 4
D6Mit11 D6Mit12 0 8

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory