Mapping Data

Experiment

• Experiment
  TEXT-Cytogenetic Localization
• Chromosome
  17
• Reference
  J:11361 Henson V, et al., Loss of heterozygosity and mitotic linkage maps in the mouse. Proc Natl Acad Sci U S A. 1991 Aug 1;88(15):6486-90
• ID
  MGI:42944

Genes

Gene	Assay Type	Description
Tcp1	Southern analysis	pB1.4
D17Tu50	Southern analysis	Tu50
Hba-ps4	Southern analysis	Y44
Pim1	Southern analysis	Pim-1A
Cryaa	Southern analysis	pMaA
H2-K1	Southern analysis	I-26
H2-D1	PCR amplified length variant	H2-DpA, H2-DpB
D17Tu49	Southern analysis	Tu49

Notes

• Experiment
  A mitotic linkage map of mouse Chromosome 17 was constructed and an order of genes was deduced from recombination within somatic cells. Mitotic recombination, chromosome loss and deletions are events which contribute to allele loss. Alleles were typed bySouthern analysis for H2-D proximal markers Tcp1, D17Tu50, Hba-ps4, Pim1, Cryaa and H2-K and for distal D17Tu49. A gene order of Tcp1 - D17Tu50 - Hba-ps4 - Pim1 - Cryaa - H2-K - H2-D was established based on 50 allele loss variant lines which were all recombinant within the Tcp1 - H2-D region. The derived mitotic map and established meiotic were colinear in this region.