Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  4
• Reference
  J:16441 Yamada Y, et al., Genetic predisposition to pre-B lymphomas in SL/Kh strain mice. Cancer Res. 1994 Jan 15;54(2):403-7
• ID
  MGI:42954

Genes

Gene	Assay Type	Description
Foc1	resistance/susceptibility
D4Mit17	PCR amplified length variant	D1
D4Mit11	PCR amplified length variant	M8

Notes

• Reference
  Authors suggest D7Kyo1 may be the Emv11 locus reported by Rowe, et al., (Science 178:861, 1972) based on its location.
• Experiment
  In the analysis of the backcross (SL/Kh x NFS/N)F1 x NFS/N, 11 of the 12 mice that developed FCC lymphomas were homozygous for the D4Mit17 recessive NFS/N allele. Six out of the 12 tumor bearing mice carried a homozygous D4Mit11 NFS/N allele. This suggests an order of centromere - Foc1 - D4Mit17 - D4Mit11.