Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  11
• Reference
  J:16681 Weinberg JB, et al., The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orally admnistered NG-monomethyl-L-arginine. J Exp Med. 1994 Feb 1;179(2):651-60
• ID
  MGI:42962

Genes

Gene	Assay Type	Description
Trp53	Southern analysis	Trp53 probe
Nos2	Southern analysis	iNOS
Thra	reported elsewhere
Erbb2	reported elsewhere

Notes

• Reference
  Authors use Nosi for Nos2.
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <c> <c> <c> <c>/<s> <s> <s> <s>
• Strain
  (C3H/HeJ-Fasl x M. spretus)F1
• Male Parent
  <c> <c> <c> <c>/<c> <c> <c> <c>
• Strain
  C3H/HeJ-Fasl/J
• Mapping Panel
  Seldin
• Allele 1
  c from C3H/HeJ-Fasl/J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Trp53	Nos2	Thra	Erbb2
59	c	c	c	c
49	s	s	s	s
2	c	s	s	s
1	s	c	c	c
2	c	c	s	s
1	s	s	c	c

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Trp53	Nos2	3	114	2.632	1.499
Nos2	Thra	3	114	2.632	1.499
Thra	Erbb2	0	114	0.000	0.000