Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  17
• Reference
  J:7210 Silver LM, et al., A diversified set of testicular cell proteins specified by genes within the mouse t complex. Cell. 1983 Nov;35(1):35-45
• ID
  MGI:42974

Genes

Gene	Assay Type
Tcp4	electrophoretic
Tcp5	electrophoretic
Tcp8	electrophoretic
Tcp9	electrophoretic
Tcp1	electrophoretic
Itpr3	visible phenotype
Tcp3	electrophoretic
Tcp6	electrophoretic
Tcp7	electrophoretic
Pgk2	electrophoretic

Notes

• Reference
  Tcp2 has been withdrawn and is replaced by Pgk2.
• Experiment
  Nine t-haplotype specific proteins were identified using two-dimensional gel electrophoresis. The expression of these proteins is directed by genes associated with mutant t-haplotypes. 129/Sv mice congenic for partial t-haplotypes were used to map the 9 protein genes within the t-complex. Tcp1, Tcp4, Tcp5, Tcp8 and Tcp9 mapped within the proximal t-complex, between the centromere and Itpr3^tf. Genes Tcp3, Tcp6 and Tcp7 mapped to the distal half of t. The t^w18 haplotype on both a 129/Sv and C3H background wasused to map Pgk2 to the distal region of the t-complex. The location of these protein genes enables their use in the identification of mutants that carry proximal or distal regions of the t-complex.