Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  2
• Reference
  J:17512 Michaud EJ, et al., A molecular model for the genetic and phenotypic characteristics of the mouse lethal yellow (Ay) mutation. Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2562-6
• ID
  MGI:43181

Genes

Gene	Allele	Assay Type	Description
Raly		PFGE	probe A
a	A^y	PFGE

Notes

• Experiment
  Using PFGE and restriction analysis, the authors were able to state both Raly and agouti probes hybridize to the same 280kb BssHII fragment. The 5' end of Raly is 280kb proximal to the 3' end of agouti and the two loci share the same transcriptional orientation. The A^y mutation is a 170kb deletion and includes most of the Raly gene except for the promoter and the noncoding first exon. The deletion starts approximately 12kb 3' of the noncoding first exon of Raly and terminates about 105kb 5' of the agouti gene.