Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  17
• Reference
  J:1783 Pilder SH, et al., A novel mouse chromosome 17 hybrid sterility locus: implications for the origin of t haplotypes. Genetics. 1991 Sep;129(1):237-46
• ID
  MGI:43353

Genes

Gene	Assay Type	Description
D17Leh54	Southern analysis	54M
Hba-ps4	Southern analysis	Hba4
Hst4	visible phenotype
Pim1	Southern analysis	PIM-1A
D17Leh89	Southern analysis	Tu89

Notes

• Experiment
  Analysis of six partial t-haplotypes indicated a male hybrid sterility locus (Hst4) mapped to mouse Chromosome 17. Males that carried partial t-haplotypes t^h18, t^s6 and t⁶ were sterile suggesting that Hst4 maps to distal inversion in(17)4 as defined by markers D17Leh54 and D17Leh89. The locus controlling the sterility phenotypes expressed by M. spretus was shown to map between Hba-ps4 and Pim1 and in M. domesticus between D17Leh54 and Pim1. Hst4 maps between Hba-ps4 and Pim1 on mouse Chromosome 17 with a gene order of D17Leh54 - Hba-ps4 - Hst4 - Pim1 - D17Leh89, and expresses three alleles in M. domesticus, M. spretus and in t-haplotypes.